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🧪 Postdoctoral Fellow Position in Molecular Chemistry – Fluorescent Nanohoops & Drug Sensing | Université de Rennes / CNRS
Institution: Institute of Chemical Sciences of Rennes (ISCR) – Université de Rennes / CNRS
📍 Location: Rennes, France 🇫🇷
💼 Position Available: Postdoctoral Fellow in Molecular Chemistry
🔬 Research Areas: Organic Chemistry | Molecular Chemistry | Supramolecular Chemistry | Fluorescent Sensors | Macrocycles | Nanohoops | Drug Detection
The Institute of Chemical Sciences of Rennes (ISCR) at Université de Rennes / CNRS is seeking a highly motivated Postdoctoral Fellow to work on an innovative research project involving water-soluble nanohoops and fluorescent sensing technologies.
The project, supported by LUMOMAT and France 2030, focuses on developing a new generation of fluorescent macrocycles capable of detecting psychoactive and performance-enhancing drugs in biological and environmental samples.
🔬 What You’ll Work On
Water-Soluble Nanohoops
The project focuses on establishing fundamental design rules for nanohoops with predictable molecular-recognition and fluorescence-emission properties.
The successful candidate will contribute to the development of innovative water-soluble, rigid, and fluorescent macrocyclic molecules.
🧪 Synthesis of Fluorescent Macrocycles
The research will involve the synthesis and investigation of eight water-soluble rigid fluorescent cycloparaphenylene (CPP) derivatives.
Key research activities will include:
- Organic synthesis of fluorescent nanohoops
- Development of water-soluble CPP derivatives
- Structural characterization
- Spectroscopic analysis
- Investigation of water-solubility properties
- Development of fluorescent molecular systems
🧬 Drug Recognition & Encapsulation
The project will investigate the ability of nanohoops to interact with and encapsulate target drug molecules.
Research activities will focus on:
- Host–guest molecular interactions
- Drug encapsulation
- Molecular recognition
- Fluorescence sensing
- Predictable recognition and emission properties
The ultimate objective is to develop nanohoops capable of functioning as effective fluorescent sensors for drug detection.
🔬 Applications in Drug Sensing
The research has important potential applications in both biomedical and environmental monitoring.
Potential applications include:
- Therapeutic monitoring of psychotropic compounds
- Detection of analgesic drugs
- Real-time sensing in biological fluids
- Drug detection in blood
- Drug detection in saliva
- Drug detection in urine
- Rapid and non-invasive screening for substance abuse
- Detection of drug residues in wastewater
🧪 Scientific Methodology
The scientific methodology will be divided into four major areas:
1️⃣ Synthesis of Water-Soluble Rigid Fluorescent Macrocycles
Design and synthesize novel water-soluble fluorescent nanohoops with controlled structural and optical properties.
2️⃣ Structural, Spectroscopic & Water-Solubility Studies
Investigate the relationship between the molecular structure of the nanohoops and their:
- Fluorescence properties
- Spectroscopic behaviour
- Water solubility
- Molecular recognition capabilities
3️⃣ Drug Encapsulation Studies
Study interactions between the developed nanohoops and target drug molecules using molecular-recognition and host–guest chemistry approaches.
4️⃣ Development of Fluorescent Sensors
Evaluate the potential of the developed molecular systems as fluorescent sensors for detecting drugs in biological and environmental samples.
🎯 Ideal Candidates
Applicants should have completed and defended their PhD within the past two years.
Candidates should possess:
- Excellent skills in organic synthesis.
- A strong background in molecular or organic chemistry.
- The ability to conduct independent scientific research.
- Strong analytical and problem-solving abilities.
- Excellent scientific communication skills.
⭐ Desirable Qualifications
Experience in the following areas would be considered an advantage:
- Spectroscopy
- Host–guest chemistry
- Supramolecular chemistry
- Molecular modelling
- Fluorescence spectroscopy
- Molecular recognition
🌟 What You’ll Gain
- Opportunity to work on innovative fluorescent nanohoop chemistry.
- Advanced experience in organic and molecular synthesis.
- Research experience in supramolecular and host–guest chemistry.
- Exposure to fluorescence-based sensing technologies.
- Opportunity to contribute to drug-detection research.
- Experience working at a leading French research institute.
- Access to an interdisciplinary scientific research environment.
- Opportunity to contribute to applications in biomedical and environmental monitoring.
💼 Position Details
Institution: Institute of Chemical Sciences of Rennes (ISCR)
Affiliation: Université de Rennes / CNRS
Research Programme: LUMOMAT + France 2030
Position: Postdoctoral Fellow in Molecular Chemistry
Project: Water-Soluble Nanohoops – A New Generation of Macrocycles for Fluorescence Sensing of Psychoactive and Performance-Enhancing Drugs
Research Focus: Organic Synthesis | Nanohoops | Fluorescent Sensors | Drug Detection | Molecular Recognition
Location: Rennes, France 🇫🇷
Contract Start: Between 1 December 2026 and 15 January 2027
📄 Candidate Requirements
Applicants should have:
Qualification: PhD in Organic Chemistry, Molecular Chemistry, Supramolecular Chemistry, or a closely related discipline.
PhD Requirement: PhD defended within the previous two years.
Essential Skills: Excellent Organic Synthesis Skills
Desirable Skills: Spectroscopy | Host–Guest Studies | Molecular Modelling
📩 How to Apply
Interested candidates are encouraged to contact the project supervisors for further information regarding the position and application process.
Contact Persons
Dr Cyril Poriel
DR CNRS
📧 Email: cyril.poriel@univ-rennes.fr
📞 Phone: +33 2 23 23 59 77
Dr Cassandre Quinton
📧 Email: cassandre.quinton@univ-rennes.fr
📍 Research Location: ISCR, Building 10C, 3rd Floor, Offices 254 and 207, Rennes, France
📌 Job Details
Institution: Institute of Chemical Sciences of Rennes (ISCR)
University: Université de Rennes
Research Organization: CNRS
Position: Postdoctoral Fellow
Location: Rennes, France 🇫🇷
Field: Molecular Chemistry | Organic Chemistry
Research Areas: Nanohoops | Fluorescent Macrocycles | Supramolecular Chemistry | Drug Sensing
Research Applications: Biomedical Drug Monitoring | Substance Abuse Screening | Environmental Monitoring
Key Research Activities: Organic Synthesis | Spectroscopy | Drug Encapsulation | Fluorescence Sensing
Qualification: PhD in a Relevant Scientific Discipline
PhD Requirement: Defended Within the Last Two Years
Essential Experience: Excellent Organic Synthesis Skills
Desirable Skills: Spectroscopy | Host–Guest Studies | Molecular Modelling
Contract Start: Between 1 December 2026 and 15 January 2027
Contact Persons: Dr Cyril Poriel | Dr Cassandre Quinton
Category
Postdoctoral Position | Postdoc Jobs | Organic Chemistry | Molecular Chemistry | Supramolecular Chemistry | Fluorescent Sensors | Nanohoops | Macrocycles | Drug Detection | Chemical Biology | Research Jobs | France Jobs
🏷️ Tags
#PostdocPosition #PostdocJobs #OrganicChemistry #MolecularChemistry #SupramolecularChemistry #Nanohoops #FluorescentSensors #DrugDetection #CNRS #UniversiteDeRennes #FranceJobs #ResearchJobs
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