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🧬 Postdoctoral Research Fellowship in Autoimmune & Inflammatory Disease | University of Pittsburgh
Institution: University of Pittsburgh
Laboratory: Sawalha Lab
📍 Location: Pittsburgh, Pennsylvania, USA
💼 Position Available: Postdoctoral Research Fellow
🔬 Research Areas: Autoimmune Disease | Inflammatory Disease | Functional Genomics | Epigenomics | Single-Cell Biology | Immunology | Bioinformatics | Genomics
The Sawalha Lab at the University of Pittsburgh is inviting applications for a Postdoctoral Research Fellowship focused on elucidating the molecular mechanisms of autoimmune and inflammatory diseases using genomic, epigenomic, and single-cell approaches.
The position offers outstanding training opportunities in translational immunology, functional genomics, and bioinformatics within a collaborative research environment.
🔬 Research Background
The Sawalha Lab investigates the molecular and cellular mechanisms underlying autoimmune and inflammatory diseases, with a particular focus on:
- Systemic lupus erythematosus (SLE)
- Behçet’s disease
- Takayasu arteritis
- Autoimmune and inflammatory disorders
- Disease-driving molecular pathways
- Translational immunology
The research integrates genomics, epigenomics, single-cell technologies, and cellular immunology to understand disease mechanisms and identify potential therapeutic targets.
🧪 Postdoctoral Research Focus
The successful candidate will lead functional genomics, epigenomics, and cellular immunology studies aimed at defining the molecular and cellular mechanisms underlying autoimmune disease.
The research will focus on patient populations previously identified by the laboratory in diseases including systemic lupus erythematosus, Behçet’s disease, Takayasu arteritis, and related immune-mediated diseases.
The candidate will have opportunities to:
- Integrate cutting-edge genomic technologies.
- Utilize single-cell transcriptomic approaches.
- Apply epigenomic approaches to autoimmune disease research.
- Perform immune repertoire analysis.
- Conduct functional genomic studies.
- Investigate disease-driving pathways.
- Analyze large-scale genomic and epigenomic datasets.
- Apply molecular and cellular biology approaches to identify therapeutic targets.
🔬 Research Methods & Approaches
The position integrates several advanced experimental and computational methodologies.
Functional Genomics & Epigenomics
Apply genomic and epigenomic approaches to investigate molecular mechanisms associated with autoimmune and inflammatory diseases.
Single-Cell Technologies
Utilize single-cell sequencing and analysis to characterize cellular populations and disease-associated molecular signatures.
Cellular Immunology
Study immune-cell populations and cellular mechanisms involved in autoimmune disease development and progression.
CRISPR-Based Approaches
Apply CRISPR-based genome editing and functional genomic approaches to investigate the biological roles of candidate genes and pathways.
Bioinformatics
Analyze and interpret complex biological datasets generated through genomic, epigenomic, and single-cell studies.
Large-Scale Data Analysis
Work with large-scale genomic and epigenomic datasets to identify molecular signatures, pathways, and potential therapeutic targets.
🎯 Ideal Candidates
The ideal candidate should have a strong academic and research background in:
- Molecular biology
- Genetics
- Immunology
- Functional genomics
- Epigenomics
- Bioinformatics
- Cellular biology
- Related biomedical sciences
Candidates should demonstrate:
- A PhD in Molecular Biology, Genetics, Immunology, or a related field.
- Completion of the PhD within 1–2 years prior to application.
- Clear interest in pursuing an independent research career in science.
- Experience with one or more relevant experimental or computational approaches.
- Strong research and analytical abilities.
- Commitment to collaborative, interdisciplinary research.
🧬 Preferred Research Experience
Applicants should have experience in one or more of the following areas:
- Functional genomics
- Epigenomics
- Bioinformatics
- Single-cell sequencing data analysis
- Flow cytometry and immune-cell phenotyping
- CRISPR-based genome and cellular biology
- Molecular biology
- Cellular immunology
- Genomic or epigenomic data analysis
Experience analyzing large-scale genomic or epigenomic datasets is highly desirable.
Candidates with a strong publication record, demonstrated scientific creativity, and a commitment to collaborative, interdisciplinary research are particularly encouraged to apply.
🌟 What You’ll Gain
Successful postdoctoral researchers will have the opportunity to:
- Work in a highly productive research laboratory.
- Gain advanced experience in functional genomics and epigenomics.
- Develop expertise in single-cell technologies.
- Receive training in translational immunology.
- Work with genomic and epigenomic datasets.
- Develop bioinformatics and computational analysis skills.
- Apply CRISPR-based approaches to biomedical research.
- Investigate molecular mechanisms of autoimmune and inflammatory diseases.
- Collaborate across interdisciplinary research areas.
- Contribute to research focused on disease mechanisms and therapeutic targets.
- Develop an independent research career in biomedical science.
📌 Research Focus
The research program focuses on understanding the molecular mechanisms of autoimmune and inflammatory diseases through the integration of:
- Functional genomics
- Epigenomics
- Genomics
- Single-cell sequencing
- Cellular immunology
- Bioinformatics
- Flow cytometry
- CRISPR-based approaches
- Molecular and cellular biology
- Immune-cell phenotyping
- Large-scale genomic data analysis
The selected postdoctoral researcher will contribute to studies of lupus, Behçet’s disease, Takayasu arteritis, and related immune-mediated diseases, with the goal of identifying disease-driving pathways and potential therapeutic targets.
💼 Anticipated Responsibilities
The selected Postdoctoral Research Fellow will be expected to:
- Lead functional genomics and epigenomics studies.
- Conduct cellular immunology research.
- Investigate molecular mechanisms underlying autoimmune diseases.
- Analyze genomic, epigenomic, and single-cell datasets.
- Apply single-cell sequencing approaches.
- Perform immune-cell phenotyping and flow cytometry.
- Utilize CRISPR-based approaches where appropriate.
- Integrate experimental and computational research approaches.
- Analyze large-scale biological datasets.
- Identify disease-associated molecular pathways.
- Contribute to collaborative interdisciplinary research.
- Develop research findings toward publications and future therapeutic applications.
📄 How to Apply
Interested candidates should submit their CV to Amr Sawalha, MD via email.
📧 Application Email
Email: asawalha@pitt.edu
Required Document: Curriculum Vitae (CV)
📍 Position Details
Institution: University of Pittsburgh
Laboratory: Sawalha Lab
Position: Postdoctoral Research Fellow
Location: Pittsburgh, Pennsylvania, USA
Research Areas: Autoimmune Disease | Inflammatory Disease | Genomics | Epigenomics | Single-Cell Biology | Immunology | Bioinformatics
Diseases of Interest: Lupus | Behçet’s Disease | Takayasu Arteritis
Key Skills: Single-Cell Sequencing | Flow Cytometry | CRISPR Editing | Bioinformatics | Genomics | Epigenomics
Qualification: PhD in Molecular Biology, Genetics, Immunology, or related field
Post-PhD Experience: Within 1–2 years of obtaining PhD
Start Date: ASAP
Application Mode: Email
Application Email: asawalha@pitt.edu
Category
Postdoctoral Position | Autoimmune Disease | Inflammatory Disease | Functional Genomics | Epigenomics | Single-Cell Sequencing | Immunology | Bioinformatics | CRISPR | Genomics | Research Jobs | Postdoc Jobs | USA Jobs | University Jobs
🏷️ Tags
#PostdoctoralPosition #PostdocJobs #UniversityOfPittsburgh #SawalhaLab #AutoimmuneDisease #InflammatoryDisease #FunctionalGenomics #Epigenomics #SingleCellSequencing #Immunology
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