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🚨 Postdoctoral Researcher | Institute Pasteur
Institution: Institute Pasteur – Biology and Genetics of the Bacterial Cell Wall Unit
📍 Location: Paris, France 🇫🇷
💼 Position Available: Postdoctoral Researcher – Microbiome / Bacterial Cell Wall Biology
🔬 Research Area: Microbiome | Helicobacter pylori | Bacterial Cell Wall Biology | Microbiology | Immunology | Organoids | Mass Spectrometry | Host–Microbe Interactions
The Institut Pasteur is inviting applications for an ANR-funded postdoctoral fellowship in the Biology and Genetics of the Bacterial Cell Wall Unit, headed by Ivo G. Boneca.
The project investigates how gut bacteria, particularly Helicobacter pylori, release peptidoglycan fragments and how these bacterial molecules influence and shape the host immune system.
The successful candidate will work in an interdisciplinary environment and collaborate with research teams from the Technical University of Munich and Monash University.
🔬 What You’ll Work On
Helicobacter pylori & Microbiome
Study how H. pylori interacts with the host and contributes to immune-system regulation through the release of peptidoglycan fragments.
Bacterial Cell Wall Biology
Investigate the mechanisms involved in the release and processing of bacterial peptidoglycan fragments and their effects on host responses.
Mass Spectrometry
Apply mass spectrometry and LC-MS/MS approaches to characterize bacterial cell-wall-derived molecules and peptidoglycan fragments.
Organoid Models
Use organoid systems to investigate host–microbe interactions and understand how bacterial molecules influence host biology.
Gut-on-Chip & In Vitro Models
Work with advanced experimental systems, including gut-on-chip platforms and in vitro models, to study bacterial–host interactions.
In Vivo Models
Use animal models to investigate the biological effects and mechanisms of bacterial peptidoglycan fragments in vivo.
Confocal Microscopy
Apply confocal microscopy and cellular imaging approaches to study bacterial interactions and immune-related processes.
🎯 Ideal Candidates
The ideal candidate should have:
- A strong background in microbiology.
- Experience or strong expertise in organoid research.
- Interest in microbiome, bacterial cell-wall biology, and host–microbe interactions.
- Experience with LC-MS/MS or mass spectrometry is an advantage.
- Experience with animal models is an advantage.
- Strong interest in studying how bacterial molecules shape host immune responses.
- Ability to work effectively in an interdisciplinary and collaborative research environment.
🌟 What You’ll Gain
- Opportunity to work at Institut Pasteur, a leading international biomedical research institution.
- Work on an ANR-funded postdoctoral research project.
- Experience investigating microbiome–host interactions and bacterial cell-wall biology.
- Training and research experience with mass spectrometry, confocal microscopy, organoids, gut-on-chip systems, and in vivo models.
- International collaboration with researchers at the Technical University of Munich and Monash University.
- Opportunity to contribute to research addressing fundamental questions in microbiology and immunology.
- Work within the Biology and Genetics of the Bacterial Cell Wall Unit, led by Ivo G. Boneca.
🧪 Research Focus
The project builds on previous research investigating the dissemination of peptidoglycan fragments across the body from the gut.
The successful postdoctoral researcher will study how Helicobacter pylori releases peptidoglycan fragments and how these molecules interact with and influence the host immune system.
The project will combine microbiology, mass spectrometry, confocal microscopy, organoid models, gut-on-chip systems, and animal models to investigate these mechanisms.
The research is conducted in collaboration with teams from the Technical University of Munich (TUM) and Monash University.
👩🔬 Key Responsibilities
The successful candidate will be expected to:
- Investigate peptidoglycan fragment release by H. pylori.
- Study the mechanisms through which bacterial molecules shape host immune responses.
- Perform experiments using in vitro, organoid, gut-on-chip, and in vivo models.
- Apply mass spectrometry and microscopy-based approaches.
- Analyze bacterial cell-wall-derived molecules and their biological effects.
- Collaborate with international research teams.
- Disseminate research findings through scientific publications and conferences.
📄 How to Apply
Interested candidates should submit their application directly to Ivo G. Boneca.
A complete application should include:
- Motivation Letter – Explaining your interest in the postdoctoral project.
- Full CV – Including academic background, research experience, publications, and relevant technical expertise.
- Minimum Two References – Contact details or references from appropriate academic/research supervisors.
📩 Apply via Email: bonecai@pasteur.fr
📌 Funding: ANR-funded Fellowship
📌 Position: Postdoctoral Researcher
📌 Location: Institut Pasteur, Paris, France
📌 Unit: Biology and Genetics of the Bacterial Cell Wall
📌 Unit Head: Ivo G. Boneca
📌 Application Documents: Motivation Letter | Full CV | Minimum 2 References
📌 Job Details
Institution: Institut Pasteur
Unit: Biology and Genetics of the Bacterial Cell Wall
Position: Postdoctoral Researcher
Funding: ANR-funded
Location: Paris, France
Research Areas: Microbiome | Helicobacter pylori | Bacterial Cell Wall Biology | Microbiology | Immunology | Host–Microbe Interactions | Organoids
Key Techniques: Mass Spectrometry | LC-MS/MS | Confocal Microscopy | Organoid Models | Gut-on-Chip | In Vivo Models
Collaborations: Technical University of Munich | Monash University
Unit Head: Ivo G. Boneca
Application: Email
Application Email: bonecai@pasteur.fr
Application Documents: Motivation Letter | Full CV | Minimum 2 References
Date on Announcement: August 25, 2026
Category
Postdoctoral Researcher | Postdoc Position | Institut Pasteur | Microbiology | Microbiome Research | Helicobacter pylori | Bacterial Cell Wall Biology | Host–Microbe Interactions | Immunology | Organoid Research | Mass Spectrometry | LC-MS/MS | Gut-on-Chip | Paris Jobs | France Research Jobs | Biomedical Research Jobs
🏷️ Tags
#PostdoctoralResearcher #PostdocPosition #InstitutPasteur #Microbiology #Microbiome #HelicobacterPylori #BacterialCellWall #Immunology #HostMicrobeInteractions #Organoids
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